Last edited by Dokazahn
Monday, May 18, 2020 | History

7 edition of Nucleoside Triphosphates and their Analogs found in the catalog.

Nucleoside Triphosphates and their Analogs

Chemistry, Biotechnology, and Biological Applications

by Morteza Vaghefi

  • 358 Want to read
  • 27 Currently reading

Published by CRC .
Written in English

    Subjects:
  • Biology, Life Sciences,
  • Cytology,
  • Nucleotides,
  • Life Sciences - Biochemistry,
  • Medical / Nursing,
  • Medical,
  • Oncology,
  • Biochemistry,
  • Science / Chemistry / Organic,
  • Derivatives,
  • Adenosine triphosphate

  • The Physical Object
    FormatHardcover
    Number of Pages408
    ID Numbers
    Open LibraryOL9593665M
    ISBN 101574444980
    ISBN 109781574444988

    Request PDF | Nucleoside Analogs in the Study of the Epitranscriptome | Over unique RNA modifications are now known including several nonstandard nucleotides present in . Background Nucleoside triphosphates participate in fundamental cellular processes as building blocks of DNA and RNA, energy carriers, and cofactors in .

      1. A process of preparing a nucleoside 5′-triphosphate of formula (I), or a derivative thereof, or a pharmaceutically acceptable salt of said nucleoside 5′-triphosphate or said derivative, wherein the Base of formula (I) is Adenine (A), Cytosine (C), Guanine (G), Thymine (T), Uracil (U), modified nucleobase or unnatural nucleobase; R 1 is H or OH, R 2 is H or OH, X is . Nucleoside Triphosphates And Their Analogs: Chemistry, Biotechnology, And Biological ApplicationsFrom CRC Press. It is the moment to boost as well as refresh your ability, knowledge as well as encounter consisted of some home entertainment for you .

    Book: Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology, and Biological Applications. ISBN: Publisher: CRC Press. Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology, and Biological Applications y una gran selección de libros, arte y artículos de .


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Nucleoside Triphosphates and their Analogs by Morteza Vaghefi Download PDF EPUB FB2

Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and Biological Applications discusses the potential of current applications and future research into context with an in-depth analysis of the role anticancer and antiviral nucleoside analogs play in medical treatments, including antiretroviral therapy regimens (for the /5(3).

Nucleoside Triphosphates and Their Analogs: Chemistry, Biotechnology, and Biological Applications features the contributions of 18 scientists from both academia and industry in the first complete source entirely dedicated to nucleoside triphosphate (NTP). The text provides collective information on the chemical, physiochemical, and biological properties of both natural and.

Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology, and Biological Applications - Kindle edition by Vaghefi, Morteza. Download it once and read it on your Kindle device, PC, phones or tablets.

Use features like bookmarks, note taking and highlighting while reading Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology, and /5(3). The book also includes experimental procedures for key reactions related to the synthesis of nucleoside analogues, providing a valuable tool for the preparation of a number of different compounds.

Throughout the book, chemical schemes and figures help readers better understand the chemical structures of nucleoside analogues and the methods used. Used extensively in cellular and molecular biology research and cytogenetic applications, nucleotide analogs are currently available for the treatment of various diseases.

Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and Biological Applications features the contributions of 18 scientists from both academia and industry in thCited by: The important principle of using antimetabolites in chemotherapy has led to the development of a series of anticancer drugs.

A list of Food and Drug Administration (FDA)-approved anticancer nucleoside analogs and their clinical indications is summarized in Table Author: Morteza Vaghefi.

Cihlar, N. Bischofberger, in Pharmacochemistry Library, Cellular Uptake. Nucleoside analogs are transported across the plasma membrane either via facilitated diffusion (e.g.

AZT) (7) or by membrane nucleoside transporters (e.g. ddC) (8).In contrast, cellular uptake of nucleoside phosphonates is slower and less efficient due to the negative charge of the phosphonate moiety.

Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and Biological Applications discusses the potential of current applications and future research into context with an in-depth analysis of the role anticancer and antiviral nucleoside analogs play in medical treatments, including antiretroviral therapy regimens (for the Price: $ nucleoside triphosphate: a nucleoside in which the H of one of the ribose hydroxyls (usually the 5') is replaced by a triphosphoric group, -PO(OH)-O-PO(OH)-O-PO(OH) 2 or the corresponding conjugate base, for example, adenosine triphosphate.

Nucleoside triphosphates and their analogs; chemistry, biotechnology, and biological applications. by Morteza M. Vaghefi. Taylor & Francis pages $ Hardcover QP Adenosine triphosphate (ATP), the first nucleoside triphosphate, was discovered in and synthesized in Get this from a library.

Nucleoside triphosphates and their analogs: chemistry, biotechnology, and biological applications. [Seyed-Morteza Monir-Vaghefi;] -- Adenosine triphosphate (ATP), the first nucleoside triphosphate, was discovered in and synthesized in Describes as the "universal currency of energy," ATP is essential to cell function in.

Nucleoside analogs as inhibitors of viral replications usually act by interaction of their triphosphates with viral polymerases.

As structural units of nucleic acids, the nucleoside triphosphates (NTPs) are the substrates for polymerase enzymes, which catalyze the polymerization of the NTPs. A nucleoside triphosphate is a molecule containing a nitrogenous base bound to a 5-carbon sugar (either ribose or deoxyribose), with three phosphate groups bound to the sugar.

They are the building blocks of both DNA and RNA, which are chains of nucleotides made through the processes of DNA replication and transcription. Nucleoside triphosphates also serve as a. Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and Biological Applications features the contributions of 18 scientists from both academia and industry in the first complete source dedicated entirely to nucleoside triphosphate (NTP).

The text provides collective information on the chemical, physiochemical, and biological 5/5(1). By reading this Nucleoside Triphosphates And Their Analogs: Chemistry, Biotechnology, And Biological ApplicationsFrom CRC Press, you can greater than what you receive from various other publication Nucleoside Triphosphates And Their Analogs: Chemistry, Biotechnology, And Biological ApplicationsFrom CRC Press This is a well-known book that is.

ISBN: OCLC Number: Description: pages: illustrations ; 24 cm: Contents: Chemical synthesis of nucleoside 5'-triphosphate / Morteza M. Vaghefi --Enzymatic synthesis of nucleoside triphosphates / Staffan Eriksson --Synthesis and properties of NTP analogs with modified triphosphate chains / Inna Koukhareva, Morteza.

Biological function. While a nucleoside is a nucleobase linked to a sugar, a nucleotide is composed of a nucleoside and one or more phosphate groups. Thus, nucleosides can be phosphorylated by specific kinases in the cell on the sugar's primary alcohol group (-CH 2-OH) to produce tides are the molecular building-blocks of DNA and RNA.

Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology and Biological Applications. Edited by Morteza Vaghefi. Gosselin, Gilles CRC Press, Boca Raton pp., hardcover $ —ISBN 1‐‐‐0 Over the past several decades, nucleoside analogues have become increasingly important in antiviral Author: Gosselin, Gilles.

A nucleoside can be defined as a nucleotide without its phosphate group. Thus, a nucleoside triphosphate (NTP) is a nucleoside bound to 3 phosphates.

This in turn must be equivalent to a nucleotide (whose name implies the inclusion of one phosphate already) plus. A nucleoside triphosphate is a molecule containing a nucleoside bound to three phosphates. Nucleotide derivatives are necessary for life, as they are the building blocks of nucleic acids and have.

It will enable researchers to choose the right method for synthesizing their nucleoside triphosphates of interest by understanding pros and cons of many available methodologies. It will keep the researchers well informed of the state-of-the-art in the nucleoside triphosphate syntheses and the pressing by: Start studying Nucleoside/Nucleotide Analogs.

Learn vocabulary, terms, and more with flashcards, games, and other study tools.ChemCyte offers a variety of non-modified and modified nucleoside triphosphates (nucleotides) and their analogs for life science, diagnostic and drug discovery research. Non-Modified Nucleoside Triphosphates.